There are several themes throughout the novel, "Of Mice and Men," but one of the main themes, is the theme of loneliness. The first line read "A few miles south of Soledad". This is quite a clever little idea by Steinbeck, since in Spanish "Soledad" means loneliness. The title "Of Mice and Men" also shows something about loneliness since the title actually came from a poem written by Robbie Burns's. The poem was called, "To …showed first 75 words of 878 total…

…showed last 75 words of 878 total…totally shown, it is a main cause for the characters loneliness. Stein beck showed how his life might have been when he lived on a ranch during the depression, and people could be very lonely. Perhaps people back then were not all lonely, but there may have been quite a few people that are portrayed in the novel. Those are the reasons that loneliness is a main theme of the novel " Of Mice and Men."